In this third update, we added 15 new randomised controlled trials (RCTs) and three new economic studies, resulting in a total of 44 RCTs (7447 included participants) and five economic studies. We carried out data extraction, assessment using the Cochrane 'Risk of bias' tool, and quality assessment according to Grading of Recommendations, Assessment, Development and Evaluations methodology. We included trials if they allocated participants to treatment randomly and compared NPWT with any other type of wound dressing, or compared one type of NPWT with another type of NPWT.Īt least two review authors independently assessed trials using predetermined inclusion criteria. There were no restrictions on language, publication date or study setting. We also searched clinical trials registries and references of included studies, systematic reviews and health technology reports. In June 2019, we searched the Cochrane Wounds Specialised Register the Cochrane Central Register of Controlled Trials (CENTRAL) Ovid MEDLINE (including In-Process & Other Non-Indexed Citations) Ovid Embase and EBSCO CINAHL Plus. To assess the effects of NPWT for preventing SSI in wounds healing through primary closure, and to assess the cost-effectiveness of NPWT in wounds healing through primary closure. Existing evidence for the effectiveness of NPWT on postoperative wounds healing by primary closure remains uncertain. Indications for the use of negative pressure wound therapy (NPWT) are broad and include prophylaxis for surgical site infections (SSIs).
0 kommentar(er)
